In vitro aminoglycoside resistance of gram-negative bacilli and staphylococci isolated from blood in Sweden 1980-1984

Scand J Infect Dis. 1986;18(3):257-63. doi: 10.3109/00365548609032335.

Abstract

The in vitro susceptibility to gentamicin, tobramycin, amikacin and netilmicin in septicaemia isolates was followed during 1980-1984 in 6-8 Swedish laboratories. The bacterial distribution was similar over the years and was dominated by Escherichia coli and staphylococci. Resistance to gentamicin was found in 2.3-3.6%, to tobramycin in 1.4-3.4%, to amikacin and netilmicin in 0.5-0.9%. Production of aminoglycoside modifying enzymes was observed among resistant strains.

MeSH terms

  • Amikacin / pharmacology*
  • Aminoglycosides / pharmacology
  • Drug Resistance, Microbial
  • Gentamicins / pharmacology*
  • Gram-Negative Bacteria / drug effects*
  • Humans
  • Kanamycin / analogs & derivatives*
  • Microbial Sensitivity Tests
  • Netilmicin / pharmacology*
  • Staphylococcus / drug effects*
  • Sweden
  • Tobramycin / pharmacology*

Substances

  • Aminoglycosides
  • Gentamicins
  • Netilmicin
  • Kanamycin
  • Amikacin
  • Tobramycin