We report a dengue outbreak in Key Largo, Florida, USA, from February through August 2020, during the COVID-19 pandemic. Successful community engagement resulted in 61% of case-patients self-reporting. We also describe COVID-19 pandemic effects on the dengue outbreak investigation and the need to increase clinician awareness of dengue testing recommendations.
Keywords: COVID-19; DENV; Dengue; Florida; SARS-CoV-2; United States; coronavirus disease; dengue virus; respiratory infections; severe acute respiratory syndrome coronavirus 2; vector-borne infections; viruses; zoonoses.