Exstrophy-Epispadias Complex

Ted Lee; Joseph Borer

doi:10.1016/j.ucl.2023.04.004

Exstrophy-Epispadias Complex

Urol Clin North Am. 2023 Aug;50(3):403-414. doi: 10.1016/j.ucl.2023.04.004. Epub 2023 May 19.

Authors

Ted Lee¹, Joseph Borer²

Affiliations

¹ Department of Urology, Boston Children's Hospital, 300 Longwood Avenue Boston, MA 02115, USA; Department of Surgery (Urology), Harvard Medical School, Boston, MA, USA. Electronic address: Ted.Lee@childrens.harvard.edu.
² Department of Urology, Boston Children's Hospital, 300 Longwood Avenue Boston, MA 02115, USA; Department of Surgery (Urology), Harvard Medical School, Boston, MA, USA.

PMID: 37385703
DOI: 10.1016/j.ucl.2023.04.004

Abstract

Exstrophy-epispadias complex encompasses a spectrum of disorders with lower abdominal midline malformations, including epispadias, bladder exstrophy, and cloacal exstrophy, also known as Omphalocele-Exstrophy-Imperforate Anus-Spinal Anomalies Complex. In this review, the authors discuss the epidemiology, embryologic cause, prenatal findings, phenotypic characteristics, and management strategies of these 3 conditions. The primary focus is to summarize outcomes pertaining to each condition.

Keywords: Bladder exstrophy; Cloacal exstrophy; Epispadias; OEIS.

Publication types

Review

MeSH terms

Bladder Exstrophy*
Epispadias* / surgery
Female
Humans
Pregnancy
Scoliosis*

Supplementary concepts

Bladder Exstrophy and Epispadias Complex