Wilms Tumor

Urol Clin North Am. 2023 Aug;50(3):455-464. doi: 10.1016/j.ucl.2023.04.008. Epub 2023 May 18.


Wilms tumor (WT), or nephroblastoma, is the most common primary malignant renal tumor of childhood. It is an embryonal tumor that develops from remnants of immature kidney. There are approximately 500 new WT cases diagnosed in the United States every year. Advances in multimodal therapy including surgery, chemotherapy, and radiation therapy given according to risk stratification have allowed most patients to achieve survival rates in excess of 90%.

Keywords: Nephrectomy; Nephroblastoma; Renal tumor; Urologic oncology; Wilms tumor.

Publication types

  • Review

MeSH terms

  • Combined Modality Therapy
  • Humans
  • Kidney
  • Kidney Neoplasms* / therapy
  • Neoplasms, Germ Cell and Embryonal*
  • Wilms Tumor* / therapy