Cyclosporine-induced erythromelalgia

Pract Neurol. 2023 Aug;23(4):343-345. doi: 10.1136/pn-2023-003770. Epub 2023 Jun 30.

Abstract

Erythromelalgia is a rare syndrome characterised by recurrent erythema, heat and burning pain in the extremities. There are two types: primary (genetic) and secondary (toxic, drug-related or associated with other diseases). We report a 42-year-old woman who developed erythromelalgia after taking cyclosporine for myasthenia gravis. Although exact mechanism for this rare adverse effect is unclear, it is reversible, and so clinicians should be aware of the association . Additional use of corticosteroids could aggravate cyclosporine's toxic effects.

Keywords: MYASTHENIA; NEUROMUSCULAR; NEUROPATHY.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cyclosporine / adverse effects
  • Erythromelalgia* / chemically induced
  • Erythromelalgia* / complications
  • Erythromelalgia* / diagnosis
  • Female
  • Humans
  • Pain

Substances

  • Cyclosporine