Time toxicity in the cancer patient is the time spent undergoing cancer-related medical care, including travel and waiting times. Oncologists don't usually include this information on sharing therapeutic decisions with patients and its impact is not generally evaluated in clinical studies. Time-related burden is most significant in patients with advanced disease and when survival is short; sometimes it may exceed the potential benefit of treatments. All relevant information should be available to the patient to enable her/him to make an informed choice. Because it is difficult to quantify the cost of time, its assessment should be included in clinical trials. Additionally, healthcare organizations should employ resources to minimize the time spent on hospital services and cancer treatments.