Mpox virus is known to be transmissible from the onset of clinical manifestations. We report the first case in Japan of a man who contracted mpox through close contact with an individual with pre-symptomatic infection. Given that transmission before symptom onset has recently been reported from various countries, the importance of prophylaxis for reducing the risk of infection and controlling the disease should be emphasized.
Keywords: Close-contact transmission; Monkeypox; Monkeypox virus; Postexposure prophylaxis; Preexposure prophylaxis.
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