Right ventricular assessment in pulmonary hypertension

Curr Opin Pulm Med. 2023 Sep 1;29(5):348-354. doi: 10.1097/MCP.0000000000000980. Epub 2023 Jul 6.

Abstract

Purpose of review: The purpose of this review is to provide an overview of assessment of right ventricular function in the context of pulmonary hypertension and pulmonary arterial hypertension (PAH). We will review unique features of right ventricular anatomy, delineation of cause of pulmonary hypertension through careful right ventricular assessment, echocardiographic and hemodynamic evaluation, and the importance of this assessment in prognosis.

Recent findings: The importance of performance in prognosis and risk assessment in patients with pulmonary hypertension has been continually emphasized in ongoing research. Representative parameters of right ventricular function have been shown to be predictive of prognosis in patients with pulmonary hypertension. Further, the importance of serial right ventricular assessment in risk assessment and prognosis has remained an emerging theme.

Summary: Careful evaluation of right ventricular function is paramount in assessing the cause of pulmonary hypertension and severity of disease. Further, it has prognostic significance, as many representative parameters of right ventricular function have been linked with mortality. In our opinion, right ventricular function should be assessed serially throughout the course of treatment in pulmonary hypertension, and baseline parameters in addition to dynamic changes should be incorporated into risk assessment. Achieving normal or near-normal right ventricular performance may serve as a principal goal in the treatment of pulmonary hypertension.

Publication types

  • Review

MeSH terms

  • Echocardiography
  • Familial Primary Pulmonary Hypertension
  • Humans
  • Hypertension, Pulmonary* / diagnostic imaging
  • Hypertension, Pulmonary* / etiology
  • Prognosis
  • Pulmonary Arterial Hypertension*
  • Ventricular Dysfunction, Right* / diagnostic imaging
  • Ventricular Dysfunction, Right* / etiology