A proposed method of grading malaria chemoprevention efficacy

Trans R Soc Trop Med Hyg. 2023 Nov 3;117(11):761-764. doi: 10.1093/trstmh/trad042.

Abstract

The efficacy and effectiveness of antimalarial drugs are threatened by increasing levels of resistance and therefore require continuous monitoring. Chemoprevention is increasingly deployed as a malaria control measure, but there are no generally accepted methods of assessment. We propose a simple method of grading the parasitological response to chemoprevention (focusing on seasonal malaria chemoprevention) that is based on pharmacometric assessment.

MeSH terms

  • Antimalarials* / therapeutic use
  • Chemoprevention / methods
  • Humans
  • Infant
  • Malaria* / drug therapy
  • Malaria* / prevention & control
  • Seasons

Substances

  • Antimalarials