Prediction of mortality in ICU patients: A comparison between the SOFA score and other indicators

Navid Shafigh; Morteza Hasheminik; Elnaz Shafigh; Haleh Alipour; Shahram Sayyadi; Neda Kazeminia; Batoul Khoundabi; Sara Salarian

doi:10.1111/nicc.12944

Prediction of mortality in ICU patients: A comparison between the SOFA score and other indicators

Nurs Crit Care. 2023 Jul 12. doi: 10.1111/nicc.12944. Online ahead of print.

Authors

Navid Shafigh¹, Morteza Hasheminik², Elnaz Shafigh³, Haleh Alipour⁴, Shahram Sayyadi⁵, Neda Kazeminia⁶, Batoul Khoundabi^{7

8}, Sara Salarian⁹

Affiliations

¹ Department of Anesthesiology and Critical Care Medicine, School of Medicine, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
² Department of Nursing, Sabzevar Branch, Islamic Azad University, Sabzevar, Iran.
³ Operative Dentistry Department, Faculty of Dentistry, AJA University of Medical Sciences, Tehran, Iran.
⁴ Department of Pediatric Pulmonology, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁵ Department of Anesthesia, Imam Hossein General Hospital, Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁶ Clinical Pharmacy Specialist, Clinical Trials and Pharmacovigilance Department, Food and Drug Administration, Tehran, Iran.
⁷ Iranian Red Crescent Society, Tehran, Iran.
⁸ Research Center for Health Management in Mass Gathering, Red Crescent Society of the Islamic Republic of Iran, Tehran, Iran.
⁹ Anesthesiology and Fellowship Critical Care Department, School of Medicine, Emam Hosein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

PMID: 37438106
DOI: 10.1111/nicc.12944

Abstract

Background: The intensive care unit (ICU) is the most important department for critically ill patients. Different scoring systems are used to assess the severity of the disease and evaluate organ failure during the patient's stay in ICU.

Aims: Our purpose was to evaluate the C-reactive protein/Albumin (CRP/Alb) ratio and SOFA score as indicators of 28-day mortality in ICU patients.

Materials and method: A total of 55 patients were enrolled in this study. CRP and CRP/Alb rates, SOFA scores, and demographic data were used to evaluate 28-day mortality in a referral hospital.

Results: Survived and dead patients were significantly different in the CRP, CRP/Alb rates, and SOFA scores. However, in the adjusted model, the SOFA score was the predictor of 28-day mortality in ICU patients.

Conclusion: SOFA score was also confirmed as a predictor of mortality in ICU patients. Besides, the role of CRP and CRP/Alb in the prediction of disease prognosis or mortality requires further studies.

Keywords: C-reactive protein; albumin; intensive care unit; mortality; prognosis.