Granulomatous reaction in lymph nodes draining laryngeal carcinoma

Head Neck Surg. 1986 Jan-Feb;8(3):214-7. doi: 10.1002/hed.2890080315.


Presented are two cases of simultaneous occurrence of epithelioid granulomas and metastatic squamous cell carcinoma in cervical lymph nodes draining supraglottic carcinoma. Laboratory tests and radiological and clinical findings ruled out sarcoidosis, as well as mycotic, mycobacterial, or other bacterial infection. Upon finding of epithelioid granulomas in cervical lymph nodes, a malignant tumor of the head and neck region should be considered as a differential diagnostic possibility. Uncritical acceptance of a diagnosis based solely on the histological appearance may lead to erroneous treatment.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Squamous Cell / pathology*
  • Female
  • Granuloma, Giant Cell / pathology*
  • Humans
  • Laryngeal Neoplasms / pathology*
  • Lymph Nodes / pathology*
  • Lymphatic Diseases / pathology*
  • Lymphatic Metastasis
  • Middle Aged
  • Neck