Artificial intelligence (AI) molecular analysis tool assists in rapid treatment decision in lung cancer: a case report

J Clin Pathol. 2023 Nov;76(11):790-792. doi: 10.1136/jcp-2023-208991. Epub 2023 Jul 18.


Leptomeningeal involvement among non-small cell lung cancer (NSCLC) patients is an aggressive form of disease that requires quick and efficient treatment. In this case report, we describe a woman in her 40s with a presenting symptom of headache that ultimately was diagnosed as leptomeningeal spread from NSCLC adenocarcinoma. We identified EGFR mutation in less than 48 hours from the biopsy using imagene-artificial intelligence's real-time algorithmic solution on the pathological diagnostic slide.

Keywords: Diagnostic Techniques and Procedures; Genes, Neoplasm; Image Processing, Computer-Assisted; LUNG CANCER.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma* / genetics
  • Adenocarcinoma* / therapy
  • Adult
  • Artificial Intelligence
  • Carcinoma, Non-Small-Cell Lung* / genetics
  • Carcinoma, Non-Small-Cell Lung* / pathology
  • Carcinoma, Non-Small-Cell Lung* / therapy
  • ErbB Receptors / genetics
  • Female
  • Humans
  • Lung Neoplasms* / diagnosis
  • Lung Neoplasms* / genetics
  • Lung Neoplasms* / therapy
  • Mutation


  • ErbB Receptors