Multidrug-resistant IgA Vasculitis with Gastrointestinal Symptoms Successfully Treated with Intravenous Cyclophosphamide and Maintained with Mycophenolate Mofetil

Intern Med. 2024 Mar 1;63(5):743-747. doi: 10.2169/internalmedicine.1990-23. Epub 2023 Jul 19.


We present the case of a 17-year-old woman with IgA vasculitis (IgAV) who presented with relapsing gastrointestinal (GI) symptoms that were refractory to glucocorticoid and combination therapy with cyclosporine A, azathioprine or mycophenolate mofetil (MMF). The patient responded well to remission induction with intravenous cyclophosphamide (IVCY) and was successfully maintained with MMF. Remission induction with IVCY followed by maintenance therapy with MMF was effective in a patient with multidrug-resistant IgAV with GI lesions.

Keywords: GI involvement; IgA vasculitis; case report; intravenous cyclophosphamide (IVCY); mycophenolate mofetil (MMF).

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Azathioprine
  • Cyclophosphamide / therapeutic use
  • Female
  • Humans
  • IgA Vasculitis*
  • Immunosuppressive Agents / therapeutic use
  • Lupus Nephritis*
  • Mycophenolic Acid / therapeutic use
  • Remission Induction


  • Mycophenolic Acid
  • Immunosuppressive Agents
  • Cyclophosphamide
  • Azathioprine