Duodenal ulcer perforation and its consequences

J Pak Med Assoc. 2023 Jul;73(7):1506-1510. doi: 10.47391/JPMA.4768.


Duodenal ulcer perforation, a frequent surgical emergency, needs simple closure with indirect Graham's Omentopexy which is effective with excellent results in majority of cases despite patients' late presentation. The objective of the study was to determine the frequency of postoperative complications of perforated duodenal ulcer, conducted in the Surgery Department, Jinnah Postgraduate Medical Centre, Karachi, from March 20, 2018 to September 20, 2018. The study was a descriptive case series of 108 patients of both genders with perforated duodenal ulcer > 1 week old with ASA score I & II. Patients with trauma and comorbidities were excluded. The patients underwent laparotomy and peritoneal toilet, and after noting the site of perforation indirect Graham's Omentopexy was performed. Complications like duodenal fistula, peritonitis, and paralytic ileus, and patient's death within 10 days of surgery were noted. Age ranged from 18 to 50 years with mean age of 35.027±5.13 years, mean weight 71.120±12.77 kg, mean height 1.541 ±0.09 metres, mean BMI 29.975±4.99 kg/m2, and the mean duration of complaint was 4.194±1.30 weeks. Male predominance in 75 (69.4%) patients. Duodenal fistula was seen in 10 (9.3%) patients, peritonitis 12 (11.1%), paralytic ileus 14 (13%) and mortality was in 11 (10.2%) patients.

Keywords: Perforated duodenal ulcer, Postoperative complications, Frequency..

MeSH terms

  • Adult
  • Duodenal Ulcer* / complications
  • Duodenal Ulcer* / epidemiology
  • Duodenal Ulcer* / surgery
  • Female
  • Fistula*
  • Humans
  • Infant
  • Male
  • Peptic Ulcer Perforation* / complications
  • Peptic Ulcer Perforation* / epidemiology
  • Peptic Ulcer Perforation* / surgery
  • Peritonitis* / complications
  • Risk Factors