Generation of control iPSC lines CBRCULi008-A and CBRCULi009-A derived from lymphoblastoid cell lines

Charles-Albert Chapotte-Baldacci; Dominic Jauvin; Mohamed Chahine

doi:10.1016/j.scr.2023.103168

Generation of control iPSC lines CBRCULi008-A and CBRCULi009-A derived from lymphoblastoid cell lines

Stem Cell Res. 2023 Sep:71:103168. doi: 10.1016/j.scr.2023.103168. Epub 2023 Jul 14.

Authors

Charles-Albert Chapotte-Baldacci¹, Dominic Jauvin¹, Mohamed Chahine²

Affiliations

¹ CERVO Brain Research Centre, Institut Universitaire en Santé Mentale de Québec, Quebec City, QC G1J 2G3, Canada; Department of Medicine, Université Laval, Quebec City, QC G1V 0A6, Canada.
² CERVO Brain Research Centre, Institut Universitaire en Santé Mentale de Québec, Quebec City, QC G1J 2G3, Canada; Department of Medicine, Université Laval, Quebec City, QC G1V 0A6, Canada. Electronic address: mohamed.chahine@phc.ulaval.ca.

PMID: 37473461
DOI: 10.1016/j.scr.2023.103168

Abstract

The generation of control human iPSC lines is important in fundamental research to understand the physiological and physiopathological mechanisms underlying human diseases. We generated and characterized two control hiPSC lines from lymphoblastoid cells collected from apparently healthy individuals. These hiPSCs display pluripotency markers, can differentiate into three embryonic germ layers, possess normal karyotypes and colony morphologies, and have no reprogramming viral vectors.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Cell Differentiation / physiology
Cell Line
Cellular Reprogramming
Humans
Induced Pluripotent Stem Cells* / metabolism