Alveolar Soft Part Sarcoma of the Tongue: A Rare Tumor at an Unusual Location

Asim Qureshi; Asem Shalaby; Khamis Al Hasani; Eiman Al-Ajmi; Fizza Qureshi; Yahya Al Badaai; Jumma Al Kasbi; Abdelhadi Shebl

doi:10.7759/cureus.40647

Alveolar Soft Part Sarcoma of the Tongue: A Rare Tumor at an Unusual Location

Cureus. 2023 Jun 19;15(6):e40647. doi: 10.7759/cureus.40647. eCollection 2023 Jun.

Authors

Asim Qureshi¹, Asem Shalaby², Khamis Al Hasani³, Eiman Al-Ajmi⁴, Fizza Qureshi⁵, Yahya Al Badaai⁶, Jumma Al Kasbi⁷, Abdelhadi Shebl⁸

Affiliations

¹ Histopathology, Sultan Qaboos University Hospital, Muscat, OMN.
² Pahtology, Sultan Qaboos University, Muscat, OMN.
³ Faculty of Dentistry, Sultan Qaboos University hospital, Muscat, OMN.
⁴ Radiology, Sultan Qaboos University Hospital, Muscat, OMN.
⁵ Dentistry, Oman Dental College, Muscat, OMN.
⁶ Otolaryngology - Head and Neck Surgery, Sultan Qaboos university Hospital, Muscat, OMN.
⁷ Otolaryngology - Head and Neck Surgery, Sultan Qaboos Comprehensive Cancer Care Center and Research Center, Muscat, OMN.
⁸ Pathology, Sultan Qaboos University, Muscat, OMN.

Abstract

Alveolar soft part sarcoma (ASPS) is a rare type of soft tissue sarcoma that typically affects adolescents and young adults, though it can occur at any age. We report a case of ASPS of the tongue, which is extremely rare at this location. The patient presented with a polypoidal lesion on the tongue, a biopsy of which showed granular and alveolar morphology. A definitive diagnosis was not rendered due to limited tissue. The case was discussed with the treating surgeon, and excision was recommended with clear margins. Excision of the lesion showed typical ASPS. A TFE-3 immunohistochemical stain was done, which showed strong immunoreactivity, thereby confirming the diagnosis of ASPS. This tumour is rare, and its presence in the tongue makes it extremely infrequent.

Keywords: alveolar soft part sarcoma; excision; polypoidal tumor; tongue; tumor imaging.

Publication types

Case Reports