One-year recovery rates for young people with depression and/or anxiety not receiving treatment: a systematic review and meta-analysis

BMJ Open. 2023 Jul 21;13(7):e072093. doi: 10.1136/bmjopen-2023-072093.

Abstract

Objectives: To systematically review 1-year recovery rates for young people experiencing depression and/or anxiety who are not receiving any specific mental health treatment.

Design: Systematic review and meta-analysis.

Data sources: MEDLINE, Embase, PsycINFO, Web of Science and Global Health were searched for articles published from 1980 through to August 2022.

Eligibility criteria: Articles were peer-reviewed, published in English and had baseline and 1-year follow-up depression and/or anxiety outcomes for young people aged 10-24 years without specific treatment.

Data extraction and synthesis: Three reviewers extracted relevant data. Meta-analysis was conducted to calculate the proportion of individuals classified as recovered after 1 year. The quality of evidence was assessed by the Newcastle-Ottawa Scale.

Results: Of the 17 250 references screened for inclusion, five articles with 1011 participants in total were included. Studies reported a 1-year recovery rate of between 47% and 64%. In the meta-analysis, the overall pooled proportion of recovered young people is 0.54 (0.45 to 0.63).

Conclusions: The findings suggest that after 1 year about 54% of young people with symptoms of anxiety and/or depression recover without any specific mental health treatment. Future research should identify individual characteristics predicting recovery and explore resources and activities which may help young people recover from depression and/or anxiety.

Prospero registration number: CRD42021251556.

Keywords: anxiety disorders; child & adolescent psychiatry; depression & mood disorders; mental health.

Publication types

  • Meta-Analysis
  • Systematic Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anxiety Disorders / epidemiology
  • Anxiety Disorders / therapy
  • Anxiety* / epidemiology
  • Depression* / epidemiology
  • Depression* / therapy
  • Humans
  • MEDLINE
  • Peer Review