Left ventricular strain echocardiography in advanced uremic cardiomyopathy compared to dilated cardiomyopathy

Rizan Mohammadi; Farnoosh Larti; Roya Sattarzadeh Badkoubeh; Maryam Mehrpooya; Akram Sardari

doi:10.1186/s43044-023-00393-y

Left ventricular strain echocardiography in advanced uremic cardiomyopathy compared to dilated cardiomyopathy

Egypt Heart J. 2023 Jul 26;75(1):67. doi: 10.1186/s43044-023-00393-y.

Authors

Rizan Mohammadi^#¹, Farnoosh Larti^#¹, Roya Sattarzadeh Badkoubeh¹, Maryam Mehrpooya¹, Akram Sardari²

Affiliations

¹ Department of Cardiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, 1419733141, Iran.
² Department of Cardiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Keshavarz Boulevard, Tehran, 1419733141, Iran. Sardaricardio@gmail.com.

^# Contributed equally.

Abstract

Background: Cardiac involvement is common in end-stage renal disease patients. The presenting study aimed to evaluate the global and segmental longitudinal strain in patients with advanced uremic cardiomyopathy (AUCM) and compare it to dilated cardiomyopathy (DCM).

Results: The mean global longitudinal strain (GLS) was significantly lower in AUCM (P value = 0.045). Comparing segmental strain showed a lower strain in mid inferoseptal (P value = 0.048), base and mid anterolateral (P value = 0.026, 0.001 respectively), base and mid anteroseptal (P value = 0.005, 0.009 respectively), base and mid inferior (P value = 0.015, 0.034 respectively) and mid anterior (P value = 0.015) in patients with AUCM compared with DCM. In both groups, the segmental strain increased from base to apex.

Conclusions: Segmental and GLSs in advanced uremic cardiomyopathy were significantly lower than those of dilated cardiomyopathy. In both groups, the segmental strain increased from base to apex.

Keywords: Dilated cardiomyopathy; End stage renal disease; Global longitudinal strain; Segmental longitudinal strain; Speckle tracking echocardiography.