Influence of temperature on the risk of gestational diabetes mellitus and hypertension in different pregnancy trimesters

Nianfeng Qian; Rongrong Xu; Yongjie Wei; Zhigang Li; Zhanshan Wang; Chen Guo; Xiaojing Zhu; Jianhao Peng; Yan Qian

doi:10.1016/j.scitotenv.2023.165713

Influence of temperature on the risk of gestational diabetes mellitus and hypertension in different pregnancy trimesters

Sci Total Environ. 2023 Nov 15:899:165713. doi: 10.1016/j.scitotenv.2023.165713. Epub 2023 Jul 24.

Authors

Nianfeng Qian¹, Rongrong Xu², Yongjie Wei², Zhigang Li², Zhanshan Wang², Chen Guo², Xiaojing Zhu², Jianhao Peng², Yan Qian³

Affiliations

¹ Beijing Haidian District Maternal and Child Health Care Hospital, Beijing, China.
² State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing, China.
³ State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing, China. Electronic address: Qianyan@craes.org.cn.

PMID: 37495151
DOI: 10.1016/j.scitotenv.2023.165713

Abstract

Previous studies have proved that exposure to extreme temperature in specific windows of pregnancy could cause some complications, such as pregnancy induced hypertension (PIH) and gestational diabetes mellitus (GDM), but differences in the effect of extreme temperature on the 2 complications are rarely studied. We carried a retrospective study on the impact of temperature on GDM/PIH in different trimesters based on data from a maternal and child health center in Beijing, China. Ambient temperatures (°C) were obtained from the China Meteorological Administration from January 1st, 2013 to May 15th, 2018. We use distributed lag non-linear models (DLNMs) combined with logistic regression to calculate the lag exposure-response relationships between the temperature and GDM/PIH from 1st to 24th/20th weeks of pregnancy. In both first and second trimesters, the risk of GDM was increased in summer with high temperatures; in second trimester, the risk of GDM increased in winter with low temperatures. In first half of pregnancy, risk of PIH was decreased in winter with low temperatures. These findings can provide the guideline for preventing the GDM and PIH induced by extreme temperature during pregnancy.

Keywords: Extreme temperature; Gestational 41 diabetes mellitus; Pregnancy-induced hypertension; Risk; Trimester.

MeSH terms

Child
Diabetes, Gestational* / epidemiology
Female
Humans
Hypertension, Pregnancy-Induced* / epidemiology
Pregnancy
Pregnancy Trimesters
Retrospective Studies
Temperature