[Pulmonary metastases in medullary cancers of the thyroid. Study of 4 cases. Originality of the lymphangitic form with amyloid stroma]

Rev Mal Respir. 1986;3(3):139-43.
[Article in French]


We studied the clinical and radiological features of pulmonary metastases present in 4 out of 22 patients with medullary carcinoma of thyroid. Two patients presented with common metastases: macronodules in one, and micronodules in the other one. The other two patients presented initially with reticulonodular perihilar lesions on chest X-ray, leading to the diagnosis of sarcoidosis in both of them. The observation of such pulmonary metastases is original: initially latent, they progress very slowly, and they correspond to a lymphangitic spread of the tumour with amyloid deposition in peribronchovascular structures without alveolar involvement, as shown in one of our cases with pathologic study.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoma / diagnostic imaging
  • Carcinoma / pathology
  • Carcinoma / secondary*
  • Female
  • Humans
  • Lung / pathology
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology
  • Lung Neoplasms / secondary*
  • Lymphangitis / etiology
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Radiography
  • Thyroid Neoplasms / pathology*