DNA Sequence of the Transposable Element IS1

Mol Gen Genet. 1979 Jan 31;169(2):213-8. doi: 10.1007/BF00271673.


The nucleotide sequence of an IS1 element recently transposed into the lacI gene is reported. This sequence is nearly identical to one previously reported for another IS1 element (Ohtsubo and Ohtsubo, 1978). The implications of this similarity are discussed. The sizes of potential polypeptides encoded in the IS1 DNA have been determined and possible roles for these peptides in the illegitimate recombination events mediated by the element are considered.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacterial Proteins / genetics
  • Base Sequence
  • DNA, Bacterial / analysis
  • DNA, Bacterial / genetics*
  • Escherichia coli / genetics*
  • Lac Operon
  • Molecular Weight
  • Peptides / genetics
  • Recombination, Genetic*
  • Translocation, Genetic


  • Bacterial Proteins
  • DNA, Bacterial
  • Peptides

Associated data

  • GENBANK/J01729