Hybrid polymer dot-magnetic nanoparticle based immunoassay for dual-mode multiplexed detection of two mycotoxins

Yi-Chen Chen; Yu-Han Syu; Jhen-Yan Huang; Chun-Yi Lin; Yang-Hsiang Chan

doi:10.1039/d3cc02586a

Hybrid polymer dot-magnetic nanoparticle based immunoassay for dual-mode multiplexed detection of two mycotoxins

Chem Commun (Camb). 2023 Aug 15;59(66):9968-9971. doi: 10.1039/d3cc02586a.

Authors

Yi-Chen Chen¹, Yu-Han Syu¹, Jhen-Yan Huang¹, Chun-Yi Lin¹, Yang-Hsiang Chan^{1

2

3}

Affiliations

¹ Department of Applied Chemistry, National Yang Ming Chiao Tung University, Hsinchu, 30010, Taiwan. yhchan@nycu.edu.tw.
² Center for Emergent Functional Matter Science, National Yang Ming Chiao Tung University, Hsinchu, 30010, Taiwan.
³ Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan.

PMID: 37501643
DOI: 10.1039/d3cc02586a

Abstract

We designed polymer dot-magnetic nanoparticle nanohybrids for signal enhancement in a test strip platform. Besides, the multicolor emissions of the Pdots embed multiplexing ability for this test strip. Two mycotoxins, aflatoxin B1 and zearalenone, were tested with the determined limits of detection of 2.15 ng mL^-1 and 4.87 ng mL^-1, respectively.

MeSH terms

Aflatoxin B1 / analysis
Food Contamination / analysis
Immunoassay
Limit of Detection
Magnetite Nanoparticles*
Mycotoxins* / analysis
Polymers
Zearalenone*

Substances

Mycotoxins
Polymers
Magnetite Nanoparticles
Zearalenone
Aflatoxin B1