Outcomes of patients with bacteriuria/pyuria of clinically undetermined significance (BPCUS) treated with antibiotics in 23 community hospital emergency departments

John J Veillette; C Dustin Waters; Jared Olson; George Vargyas; Emily M Ingalls; Mary A Hutton; Nick Tinker; Stephanie S May; Rachel A Foster; Jena Stallsmith; Todd J Vento

doi:10.1017/ash.2023.204

Outcomes of patients with bacteriuria/pyuria of clinically undetermined significance (BPCUS) treated with antibiotics in 23 community hospital emergency departments

Antimicrob Steward Healthc Epidemiol. 2023 Jun 30;3(1):e114. doi: 10.1017/ash.2023.204. eCollection 2023.

Authors

John J Veillette^{1

2}, C Dustin Waters³, Jared Olson^{4

5}, George Vargyas⁶, Emily M Ingalls², Mary A Hutton⁷, Nick Tinker², Stephanie S May^{1

2}, Rachel A Foster², Jena Stallsmith^{4

5}, Todd J Vento^{1

8}

Affiliations

¹ Infectious Diseases Telehealth Service, Intermountain Healthcare, Murray, UT, USA.
² Department of Pharmacy, Intermountain Medical Center, Murray, UT, USA.
³ Department of Pharmacy, McKay-Dee Hospital, Ogden, UT, USA.
⁴ Department of Pharmacy, Primary Children's Hospital, Salt Lake City, UT, USA.
⁵ Division of Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City, UT, USA.
⁶ Utah Emergency Physicians, Intermountain Medical Center Emergency Department, Murray, UT, USA.
⁷ Department of Pharmacy, Utah Valley Medical Center, Provo, UT, USA.
⁸ Division of Clinical Epidemiology and Infectious Diseases, Intermountain Medical Center, Murray, UT, USA.

Abstract

The optimal management of bacteriuria/pyuria of clinically undetermined significance (BPCUS) is unknown. Among 220 emergency department patients prescribed antibiotics for BPCUS, we found frequent readmissions, which were mitigated by outpatient follow-up visits. Observation and follow-up for an unknown diagnosis should be emphasized over antibiotics due to high likelihood of readmissions.