In AF, the effects of DOACs vs. warfarin on death and stroke/systemic embolism vary by baseline CrCl level

Stephanie Carlin; James Douketis

doi:10.7326/J23-0054

In AF, the effects of DOACs vs. warfarin on death and stroke/systemic embolism vary by baseline CrCl level

Ann Intern Med. 2023 Aug;176(8):JC91. doi: 10.7326/J23-0054. Epub 2023 Aug 1.

Authors

Stephanie Carlin¹, James Douketis¹

Affiliation

¹ McMaster University, Hamilton, Ontario, Canada (S.C., J.D.).

PMID: 37523701
DOI: 10.7326/J23-0054

Abstract

Harrington J, Carnicelli AP, Hua K, et al. Direct oral anticoagulants versus warfarin across the spectrum of kidney function: patient-level network meta-analyses from COMBINE AF. Circulation. 2023;147:1748-1757. 37042255.

Publication types

Comment

MeSH terms

Administration, Oral
Anticoagulants / adverse effects
Atrial Fibrillation* / complications
Atrial Fibrillation* / drug therapy
Embolism*
Humans
Stroke*
Warfarin / adverse effects

Substances

Anticoagulants
Warfarin