The clinical findings to notice mild elevation of intracranial pressure in an otology clinic

Am J Otolaryngol. 2023 Nov-Dec;44(6):104004. doi: 10.1016/j.amjoto.2023.104004. Epub 2023 Jul 17.

Abstract

Mildly elevated intracranial pressure appears to be a distinct pathology separate from idiopathic increased intracranial pressure and migraine. Many patients present with head fullness-pressure and dizziness, which is often suggestive of a clinical diagnosis of vestibular migraine. These patients may additionally have episodic vertigo as seen in endolymphatic hydrops and positional vertigo in addition to feeling dizzy. In most cases, hearing is normal. A long duration of the condition or a presence of associated ear pathologies, i.e., dehiscence, fistula, hypermobile footplate, or history of chronic ear infections can add hearing loss to clinical presentations. Low-pitch pulsatile tinnitus, when present, is an important symptom. The neuroimaging findings such as partially empty sella, blockage of the dural venous sinus or sigmoid sinus wall defects are frequently observed. The condition is diagnosed by measuring the lumbar puncture opening pressure. Typically, patients have normal cerebrospinal fluid chemistry and microscopy. Lowering the pressure during the lumbar puncture will resolve the patient's symptoms temporarily. Medical therapy is typically successful using carbonic anhydrase inhibitors and corrections of medical disorders that may be contributing to the increased pressure. A few require shunting or stenting procedures. In this review article, we define the condition in detail with illustrative cases that we collected from our practices.

Keywords: Benign positional vertigo; Dizziness; Episodic vertigo; IIH; Idiopathic increased intracranial pressure; Low pitch pulsatile tinnitus; Migraine; Mildly elevated intracranial pressure; Pulsatile tinnitus; Vertigo; Vestibular migrane.

Publication types

  • Review

MeSH terms

  • Endolymphatic Hydrops*
  • Humans
  • Intracranial Hypertension* / complications
  • Intracranial Hypertension* / diagnosis
  • Intracranial Pressure
  • Migraine Disorders*
  • Vertigo