An optofluidic sensor based on a Bragg grating in hollow-core fiber (HCF) is experimentally demonstrated. The grating is inscribed into the HCF by femtosecond laser illumination through a phase mask. Periodic index modulation is introduced into the silica material surrounding the hollow core, causing cladding mode resonance, and multiple reflection peaks are observed in the grating spectrum. These reflection peaks later shift to longer wavelengths when high-index liquid is infiltrated into the HCF. The new reflection peak results from the backward coupling of the liquid core mode of the waveguide, the mode field of which overlaps with the grating modulation surrounding the liquid core. The resonant wavelength of the liquid-core fiber grating increases with the index value of the infiltrating liquid, and optofluidic refractive index sensing is realized with the device. The highest refractive index sensitivity, 1117 nm/RIU, is obtained experimentally in the index range of 1.476-1.54. The infiltrated hollow-core fiber Bragg grating also exhibits high temperature sensitivity due to the high thermal-optic coefficient of the liquid, and a sensitivity of -301 pm/°C is achieved in the temperature range of 25°C to 60°C.