The influence of political ideology on awareness of HPV and HPV vaccine among adults in the United States

Hum Vaccin Immunother. 2023 Aug 1;19(2):2232706. doi: 10.1080/21645515.2023.2232706.


This study aimed to investigate the association between political ideology and awareness of HPV and HPV vaccine among US adults. Study data were derived from Health Information National Trends Survey 5 Cycle 4, a 2020 cross-sectional survey of US adults. Multivariable logistic regressions were conducted to examine the association between political ideology with HPV and HPV vaccine awareness. A total of 3418 adults participated in the study, with the majority being non-Hispanic White individuals and women. The results showed that 66.1% and 62.3% of the participants were aware of HPV and HPV vaccine, respectively. A total of 36.9%, 29.7% and 33.4% of the population reported moderate, liberal and conservative political ideologies respectively. Awareness levels were highest among liberals, with 77.1% and 72.7% reporting awareness of HPV and HPV vaccine respectively. Multivariable logistic regression analysis revealed that liberal participants were more likely to be aware of HPV (aOR, 1.94; 95% CI, 1.25-3.00), and HPV vaccines (aOR, 1.94; 95% CI, 1.37-2.74) compared to moderates. Also, liberals had higher odds of HPV (aOR, 2.41; 95% CI, 1.65-3.51), and HPV vaccine awareness (aOR, 1.91; 95% CI, 1.29-2.83) compared to conservatives. However, there was no significant difference in awareness between moderates and conservatives. Study findings point to an association between individuals' political ideology and HPV awareness. Further research is needed to understand the intricacies on how political ideology impacts HPV awareness. Overall, results highlight the need to incorporate individuals' political ideologies in interventions geared toward increasing the awareness and uptake of HPV vaccination.

Keywords: HPV awareness; HPV vaccination; HPV vaccine awareness; Political ideology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Female
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Papillomavirus Infections* / prevention & control
  • Papillomavirus Vaccines*
  • Surveys and Questionnaires
  • United States
  • Vaccination
  • White


  • Papillomavirus Vaccines