The Practice of Enteral Nutrition: Clinical Evidence for Feeding Protocols

Ariel A Salas; Colm P Travers

doi:10.1016/j.clp.2023.04.005

The Practice of Enteral Nutrition: Clinical Evidence for Feeding Protocols

Clin Perinatol. 2023 Sep;50(3):607-623. doi: 10.1016/j.clp.2023.04.005. Epub 2023 May 26.

Authors

Ariel A Salas¹, Colm P Travers²

Affiliations

¹ Division of Neonatology, Department of Pediatrics, Heersink School of Medicine, University of Alabama at Birmingham, 1700 6th Avenue South Women & Infants Center Suite 9380, Birmingham, AL 35233, USA. Electronic address: asalas@uab.edu.
² Division of Neonatology, Department of Pediatrics, Heersink School of Medicine, University of Alabama at Birmingham, 1700 6th Avenue South Women & Infants Center Suite 9380, Birmingham, AL 35233, USA.

Abstract

Establishing full enteral nutrition in critically ill preterm infants with immature gastrointestinal function is challenging. In this article, we will summarize emerging clinical evidence from randomized clinical trials suggesting the feasibility and efficacy of feeding interventions targeting the early establishment of full enteral nutrition. We will also examine trial outcomes of higher volume feedings after the establishment of full enteral nutrition. Only data from randomized clinical trials will be discussed extensively. Future opportunities for clinical research will also be presented.

Keywords: Enteral feeding; Growth; Infant; Newborn; Nutrition; Premature infants; Preterm; Randomized trials.

Publication types

Research Support, N.I.H., Extramural
Review

MeSH terms

Clinical Trials as Topic
Enteral Nutrition* / methods
Humans
Infant, Newborn
Infant, Premature*

Abstract

Publication types

MeSH terms

Grants and funding