Who Is at Risk for New Hepatitis B Infections Among People With HIV?

Open Forum Infect Dis. 2023 Jul 17;10(8):ofad375. doi: 10.1093/ofid/ofad375. eCollection 2023 Aug.


Hepatitis B virus (HBV) increases morbidity and mortality among people with HIV (PWH). We retrospectively analyzed HBV incidence among 5785 PWH. Fourteen had newly positive hepatitis B s antigen (mean 5.2 person-years of follow-up, 46.4/100 000 infections/year). These data show gaps in HBV vaccination and in the preventative efficacy of HBV-specific antiretroviral therapy.

Keywords: HBV; HBV vaccination; HIV; incident HBV infection.