Cytological features of chordoid glioma: A case report with summary of prior published cases

Diagn Cytopathol. 2023 Nov;51(11):E314-E316. doi: 10.1002/dc.25207. Epub 2023 Aug 4.

Abstract

Chordoid glioma is an uncommon low-grade glioma and is a CNS WHO grade 2 tumour in the current WHO 2021 classification. Predominantly it is seen in the third ventricle and in young adults. Although the histological features of chordoid glioma are well documented, there is sparse literature describing its cytological features. Here we describe the squash cytological features of a case of chordoid glioma along with summary of prior published cases. The smears tend to be quite cellular, the cells show mild pleomorphism, anisonucleosis, and absent mitotic activity. The background shows a distinctive bluish myxoid stroma. It can be mistaken for high grade glioma on squash cytology.

Keywords: CNS tumours; chordoid glioma; squash cytology.

Publication types

  • Case Reports

MeSH terms

  • Cerebral Ventricle Neoplasms* / pathology
  • Cytodiagnosis
  • Glioma* / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Third Ventricle* / pathology
  • Young Adult