Snapshot: Choroid plexus brain barrier

Sivan Gelb; Maria K Lehtinen

doi:10.1016/j.cell.2023.07.015

Snapshot: Choroid plexus brain barrier

Cell. 2023 Aug 3;186(16):3522-3522.e1. doi: 10.1016/j.cell.2023.07.015.

Authors

Sivan Gelb¹, Maria K Lehtinen²

Affiliations

¹ Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
² Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA. Electronic address: maria.lehtinen@childrens.harvard.edu.

PMID: 37541203
DOI: 10.1016/j.cell.2023.07.015

Abstract

Located in each brain ventricle, choroid plexus (ChP) tissue forms a blood-CSF barrier and produces cerebrospinal fluid (CSF) and other supportive factors. Sheets of ChP epithelial cells enclose a vascularized stroma of mesenchymal, immune, and neuron/glia-like cells. Burgeoning ChP studies are revealing its complex set of functions across the lifespan. To view this SnapShot, open or download the PDF.

Publication types

Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural

MeSH terms

Blood-Brain Barrier
Brain*
Cerebrospinal Fluid
Choroid Plexus*
Epithelial Cells
Longevity