Cannflavin A and B, prenylated flavones from Cannabis sativa L

Experientia. 1986 Apr 15;42(4):452-3. doi: 10.1007/BF02118655.

Abstract

Two novel prenylated flavones, termed Cannflavin A and B, were isolated from the cannabinoid free ethanolic extract of Cannabis sativa L. Both compounds inhibited prostaglandin E2 production by human rheumatoid synovial cells in culture.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arthritis, Rheumatoid / metabolism
  • Cannabis / analysis*
  • Flavones
  • Humans
  • Plant Extracts / isolation & purification*
  • Plant Extracts / pharmacology
  • Prostaglandin Antagonists / isolation & purification*
  • Prostaglandins E / biosynthesis
  • Structure-Activity Relationship
  • Synovial Fluid / drug effects
  • Synovial Fluid / metabolism

Substances

  • Flavones
  • Plant Extracts
  • Prostaglandin Antagonists
  • Prostaglandins E
  • cannflavin