Renal sarcoidosis presenting with chronic kidney disease and hypercalcemia

Clin Nephrol. 2023 Oct;100(4):177-180. doi: 10.5414/CN111115.

Abstract

Sarcoidosis is a multisystem inflammatory disease that most frequently affects the lungs, lymph nodes, eyes, and skin. Renal involvement is clinically rare. We describe a 72-year-old male who presented with chronic kidney disease and elevated serum calcium and angiotensin-converting enzyme. Renal biopsy pathology showed chronic granulomatous interstitial nephritis. Renal function was significantly improved after glucocorticoid therapy. This case emphasizes that chronic kidney disease and hypercalcemia can be clues for renal sarcoidosis. Early renal biopsy and projective treatment is beneficial for renal outcome.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Humans
  • Hypercalcemia* / diagnosis
  • Hypercalcemia* / etiology
  • Kidney / pathology
  • Male
  • Nephritis, Interstitial* / pathology
  • Peritoneal Diseases*
  • Renal Insufficiency, Chronic* / complications
  • Renal Insufficiency, Chronic* / diagnosis
  • Renal Insufficiency, Chronic* / pathology
  • Sarcoidosis* / complications
  • Sarcoidosis* / diagnosis
  • Sarcoidosis* / drug therapy