Identification of a putative second T-cell receptor

Nature. 1986 Jul 10-16;322(6075):145-9. doi: 10.1038/322145a0.


Framework monoclonal antibodies have identified a population of human lymphocytes that express the T3 glycoprotein but not the T-cell receptor (TCR) alpha- and beta-subunits. Chemical crosslinking experiments reveal that these lymphocytes express novel T3-associated polypeptides, one of which appears to be the product of the T gamma gene. The other polypeptide may represent a fourth TCR subunit, designated T delta.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antibodies, Monoclonal
  • Cell Line
  • DNA
  • Electrophoresis
  • Humans
  • Immunologic Deficiency Syndromes / immunology
  • Nucleic Acid Hybridization
  • Receptors, Antigen, T-Cell / analysis*


  • Antibodies, Monoclonal
  • Receptors, Antigen, T-Cell
  • DNA