Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Oct 1;158(10):1105-1106.
doi: 10.1001/jamasurg.2023.2756.

Long-Term Outcome of Nonoperative Treatment of Appendicitis

Barbora Pátková  1   2 , Anna Svenningsson  1   3 , Markus Almström  1   3 , Jan F Svensson  1   3 , Staffan Eriksson  4   5 , Tomas Wester  1   3 , Simon Eaton  6
Affiliations

Long-Term Outcome of Nonoperative Treatment of Appendicitis

Barbora Pátková et al. JAMA Surg. .
No abstract available

Plain language summary

This cohort study uses registry data to report the long-term outcomes of patients who participated in randomized clinical trials of antibiotics vs surgery in Sweden in the 1990s.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: Dr Svensson reported receiving grants from Lovisa Foundation during the conduct of the study. No other disclosures were reported.

Figures

Figure 1.
Figure 1.. Flow Diagram of Follow-Up of the Initial Cohort
RCTs indicates randomized clinical trials.
Figure 2.
Figure 2.. Cumulative Incidence of Appendectomy Among Patients in the Nonoperative Treatment Group up to 25-Year Follow-Up
Shaded area represents 95% CI.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Salminen P, Tuominen R, Paajanen H, et al. . Five-year follow-up of antibiotic therapy for uncomplicated acute appendicitis in the APPAC Randomized Clinical Trial. JAMA. 2018;320(12):1259-1265. doi:10.1001/jama.2018.13201 - DOI - PMC - PubMed
    1. Eriksson S, Granström L. Randomized controlled trial of appendicectomy versus antibiotic therapy for acute appendicitis. Br J Surg. 1995;82(2):166-169. doi:10.1002/bjs.1800820207 - DOI - PubMed
    1. Styrud J, Eriksson S, Nilsson I, et al. . Appendectomy versus antibiotic treatment in acute appendicitis: a prospective multicenter randomized controlled trial. World J Surg. 2006;30(6):1033-1037. doi:10.1007/s00268-005-0304-6 - DOI - PubMed

Publication types

Substances