The relationship between CTA performances and cardiac function indicators in myocardial bridge and mural coronary artery

Fuzhen Guo; Junfen Yan; Xiubin Xue

The relationship between CTA performances and cardiac function indicators in myocardial bridge and mural coronary artery

Am J Transl Res. 2023 Jul 15;15(7):4779-4787. eCollection 2023.

Authors

Fuzhen Guo¹, Junfen Yan², Xiubin Xue³

Affiliations

¹ Department of Emergency, The First Hospital of Zhangjiakou Zhangjiakou 075000, Hebei, China.
² Department of Gastroenterology, Hebei Huaao Hospital Zhangjiakou 075000, Hebei, China.
³ Department of Radiology, The First Hospital of Zhangjiakou Zhangjiakou 075000, Hebei, China.

PMID: 37560240
PMCID: PMC10408538

Abstract

Objective: To investigate the relationship between computed tomography angiography (CTA) performances and cardiac function indicators in patients with myocardial bridge and mural coronary artery (MB-MCA).

Methods: The clinical data of 60 patients with MB-MCA receiving CTA in the First Hospital of Zhangjiakou from January 2021 to February 2022 were analyzed retrospectively. The patients were divided into different groups based on CTA performances, including the degree of stenosis of the left anterior descending (LAD) MCA, whether there was atherosclerosis in the anterior segment of MB of LAD branch, the MB thickness, and the degree of stenosis of the LAD branch. The correlation between these TCA performances and cardiac function indicators including end-systolic volume (ESV), end-diastolic volume (EDV), stroke volume (SV), cardiac output (CO), and left ventricular ejection fraction (LVEF) was analyzed. Besides, the receiver operating characteristic (ROC) curve was used to analyze the predictive performance of cardiac function indicators for the severity of MB-MCA.

Results: ESV, EDV, SV, CO and LVEF were statistically different between the moderate stenosis group and mild stenosis group (all P < 0.05). EDV, SV, CO, and LVEF were statistically different between the atherosclerosis group and non-atherosclerosis group (all P < 0.05). SV, CO, LVEF in the deep group were lower than that in the superficial group (all P < 0.05). EDV, CO, LVEF were different between the LAD moderate stenosis group and LAD mild stenosis group (all P < 0.05). The AUC (areas under the curve) of combined detection of ESV, EDV, SV, CO, and LVEF in predicting the severity of MB-MCA was 0.907, which was higher than the single indicator predictive effect.

Conclusions: Cardiac function indicators, mainly CO and LVEF are correlated with the CTA performance of MB-MCA patients. The combination of cardiac function indicators has a good effect in predicting the severity of MB-MCA.

Keywords: CTA performances; cardiac function indicators; myocardial bridge and mural coronary artery.