[The role of succinic acid in neuron reaction to synaptic activation]

Biofizika. 1986 Jul-Aug;31(4):631-3.
[Article in Russian]

Abstract

It has been shown on Retzius neuron of the leech that after preintroduction of sodium succinate the reaction to synaptic stimulation expressed in increased frequency of the impulse activity proceeds more intensively than in the norm. In connection with the fact that against the background of succinate effect reaction to acetylcholine increases it is suggested that this very mediator is responsible for slower decrease of the impulse activity frequency at synaptic activation.

Publication types

  • English Abstract

MeSH terms

  • Acetylcholine / pharmacology
  • Electric Stimulation
  • In Vitro Techniques
  • Leeches
  • Membrane Potentials / drug effects
  • Neurons / drug effects
  • Neurons / physiology*
  • Serotonin / pharmacology
  • Succinates / metabolism
  • Succinates / pharmacology*
  • Synapses / drug effects
  • Synapses / physiology*

Substances

  • Succinates
  • Serotonin
  • Acetylcholine