Improvement of Sensitivity and Speed of Virus Sensing Technologies Using nm- and μm-Scale Components

Sensors (Basel). 2023 Jul 31;23(15):6830. doi: 10.3390/s23156830.

Abstract

Various viral diseases can be widespread and cause severe disruption to global society. Highly sensitive virus detection methods are needed to take effective measures to prevent the spread of viral infection. This required the development of rapid virus detection technology to detect viruses at low concentrations, even in the biological fluid of patients in the early stages of the disease or environmental samples. This review describes an overview of various virus detection technologies and then refers to typical technologies such as beads-based assay, digital assay, and pore-based sensing, which are the three modern approaches to improve the performance of viral sensing in terms of speed and sensitivity.

Keywords: beads-based assay; digital assay; pore-based assay; virus detection.

Publication types

  • Review

MeSH terms

  • Humans
  • Virus Diseases* / diagnosis
  • Viruses* / isolation & purification

Grants and funding

This research received no external funding.