The continuing need for therapeutic agents for respiratory syncytial virus infection

Antivir Chem Chemother. 2023 Jan-Dec:31:20402066231194424. doi: 10.1177/20402066231194424.

Abstract

Respiratory syncytial virus infections recur throughout life despite induction of immunity by the first natural infection. An effective vaccine has long been sought but no vaccine is currently licensed, although promising candidates are currently being developed based on greater knowledge of the virus properties. However, there are significant populations that may not be protected adequately by a vaccine or are unable to be vaccinated. Thus, there is a continued need for effective therapeutic agents to treat the infection, especially in higher-risk individuals, a perspective presented in this article.

Keywords: Respiratory syncytial virus; antiviral agents; susceptibility to infection; therapeutic agents; vaccines.

MeSH terms

  • Humans
  • Respiratory Syncytial Virus Infections*
  • Respiratory Syncytial Virus Vaccines*
  • Respiratory Syncytial Virus, Human*

Substances

  • Respiratory Syncytial Virus Vaccines