Activated Tryptophan-Kynurenine metabolic system in the human brain is associated with learned fear

Maria Rita Battaglia; Chiara Di Fazio; Simone Battaglia

doi:10.3389/fnmol.2023.1217090

Activated Tryptophan-Kynurenine metabolic system in the human brain is associated with learned fear

Front Mol Neurosci. 2023 Jul 28:16:1217090. doi: 10.3389/fnmol.2023.1217090. eCollection 2023.

Authors

Maria Rita Battaglia¹, Chiara Di Fazio², Simone Battaglia^{2

3}

Affiliations

¹ Istituto di Ricovero e Cura a Carattere Scientifico Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola, Bologna, Italy.
² Department of Psychology, Center for Studies and Research in Cognitive Neuroscience, University of Bologna, Bologna, Italy.
³ Department of Psychology, University of Turin, Turin, Italy.

No abstract available

Keywords: KYN pathway; PFC-dependent cognition; Tryptophan-Kynurenine pathway; fear conditioning; learned fear; neuropsychiatric disorders; prefrontal cortex (PFC).

Grants and funding

This work was supported by #NEXTGENERATIONEU (NGEU) and funded by the Ministry of University and Research (MUR), National Recovery and Resilience Plan (NRRP), project MNESYS (PE0000006)—A multiscale integrated approach to the study of the nervous system in health and disease (DN. 1553 11.10.2022) to SB.