Testing and Case Rates of Gonorrhea, Chlamydia, Syphilis, and HIV among People with Substance Use Disorders in the Veterans Health Administration

J Addict Med. 2023 Jul-Aug;17(4):387-393. doi: 10.1097/ADM.0000000000001134. Epub 2023 Jan 12.

Abstract

Background: Little is known about national patterns of sexually transmitted infection (STI) testing and infections among people with substance use disorders (SUDs).

Methods: This study used a national retrospective analysis of people with SUDs receiving healthcare in the Veterans Health Administration in 2019 (N = 485,869). We describe testing rates, test positivity, and case rates for gonorrhea, chlamydia, syphilis, and HIV among individuals with alcohol, opioid, cocaine, and noncocaine stimulant use disorders in a national cohort of Veterans Health Administration patients.

Results: Test and case rates for all STIs were highest among people with noncocaine stimulant use. People with alcohol use disorder had the lowest testing rates but intermediate incidence for all STIs. People with multiple SUDs had higher incidence of all STIs than those with single SUDs. Mental health diagnoses and houselessness were common. The HIV test positivity was 0.14% to 0.36% across SUD groups.

Conclusions: Sexually transmitted infection testing rates between SUD groups were discordant with their respective case rates. High STI rates in people with SUDs suggest a need for more comprehensive testing, particularly for those with noncocaine stimulant use and those with comorbid houselessness or mental health diagnoses.

MeSH terms

  • Chlamydia*
  • Gonorrhea* / diagnosis
  • Gonorrhea* / epidemiology
  • HIV Infections* / diagnosis
  • HIV Infections* / epidemiology
  • Humans
  • Retrospective Studies
  • Sexually Transmitted Diseases* / diagnosis
  • Sexually Transmitted Diseases* / epidemiology
  • Substance-Related Disorders* / epidemiology
  • Syphilis* / diagnosis
  • Syphilis* / epidemiology
  • Veterans Health