Drug-Induced Thrombocytopenia: A Case Involving Vancomycin

Abstract

Drug-induced thrombocytopenia (DIT) is a rare adverse effect that occurs when administering various medications. The medications associated with this possible adverse effect include heparin, penicillin, furosemide, vancomycin, non-steroidal anti-inflammatory drugs, ranitidine, and many others. DIT causes a rapid decrease in platelet counts after drug administration and typically resolves once the offending agent has been discontinued. The induced thrombocytopenia increases the bleeding risk and possibility of adverse effects throughout a hospital course. In this case report, we look at the presenting symptoms and treatment course of an interesting case of DIT that occurred following the administration of vancomycin.

Keywords: drug discontinuation; drug-induced thrombocytopenia; immune-mediated thrombocytopenia; vancomycin infusion; vancomycin-induced immune thrombocytopenia.