Ultrasound-guided selective supraclavicular nerve block for postoperative pain control in children receiving Hickman catheter or chemoport insertion: A randomized controlled trial

Paediatr Anaesth. 2024 Jan;34(1):35-41. doi: 10.1111/pan.14745. Epub 2023 Aug 16.

Abstract

Background: Optimal pain management after insertion of a central venous catheter in children remains unclear.

Aim: This study aimed to evaluate the effects of a selective supraclavicular nerve block on postoperative analgesia in pediatric patients undergoing hickman catheter or chemoport insertion.

Methods: Fifty patients aged 3-18 years scheduled for elective Hickman or chemoport insertion were randomized into two groups of 25 each: one group received an ultrasound-guided selective supraclavicular nerve block with 0.1 mL/kg of 0.5% ropivacaine (SSCNB group), and the other group did not receive a nerve block (control group). The primary outcome was the postoperative Wong-Baker Faces Pain Rating Scale score measured between 10 and 30 min after surgery. Secondary outcomes included pain scores at 1, 3, and 24 h after the surgery, block-related complications, length of stay in the postanesthesia care unit, postoperative analgesic consumption, and time to first analgesic use 24 h after surgery.

Results: The worst pain score within 30 min in the recovery room was significantly lower in the SSCNB group compared to the control group (6 [5-7] vs. 3 [2-4]; median difference, -3; 95% CI, -4 to -1; p < .001). Pain scores at 1, 3, and 24 h after surgery were also significantly lower in the SSCNB group. The need for both opioid and non-opioid analgesics in the postoperative period was significantly lower in the SSCNB group (36.0% vs. 0%; p = .002 and 44.0% vs. 16.0%; mean difference, -28%; 95% CI, -56 to 0.19; p = .033, respectively), while other secondary outcomes were not significantly different between the two groups.

Conclusions: Ultrasound-guided SSCNB is an effective method for managing postoperative pain in children undergoing Hickman catheter or chemoport insertion, reducing the need for analgesics within 24 h after surgery.

Trial registration: ClinicalTrials.gov NCT05015907.

Keywords: analgesia; central venous catheterization; children; nerve block.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analgesics
  • Analgesics, Opioid
  • Anesthetics, Local / therapeutic use
  • Brachial Plexus Block* / adverse effects
  • Central Venous Catheters* / adverse effects
  • Child
  • Humans
  • Postoperative Pain / drug therapy
  • Postoperative Pain / etiology
  • Ultrasonography, Interventional / methods

Substances

  • Anesthetics, Local
  • Analgesics
  • Analgesics, Opioid

Associated data

  • ClinicalTrials.gov/NCT05015907