Factors associated with visual acuity improvement with a binocular digital therapeutic for amblyopia

J AAPOS. 2023 Oct;27(5):300-303. doi: 10.1016/j.jaapos.2023.06.007. Epub 2023 Aug 21.


We combined data from 121 amblyopic children enrolled in two prospective open-label pilot studies and a randomized trial of a binocular digital therapeutic to identify factors associated with positive response to amblyopia treatment. Visual acuity improved ≥1 line in 81% of participants after 12 weeks of therapy. Treatment response was not found to be associated with age, severity of amblyopia, or prior treatment status. Although these findings may suggest broad efficacy for this treatment approach, further investigation in larger cohorts is needed to identify factors associated with treatment response.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amblyopia* / therapy
  • Child
  • Child, Preschool
  • Follow-Up Studies
  • Humans
  • Prospective Studies
  • Treatment Outcome
  • Video Games*
  • Vision, Binocular / physiology
  • Visual Acuity