A rapid enzyme immunoassay for the detection of IgM rheumatoid factor--a comparison of "sero-negative" and "sero-positive" rheumatoid patients

J Clin Lab Immunol. 1986 Aug;20(4):207-9.


The ELISA technique for measuring RF is a reliable, low cost, quick method which has adequate specificity and improved sensitivity over other methods. This last property plus its flexible potential for measuring RF in classes other than IgM should make it a particularly useful tool in assessing "sero-negative" patients, while in the long run its routine use should supersede that of the other tests.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arthritis, Rheumatoid / blood*
  • Enzyme-Linked Immunosorbent Assay*
  • Female
  • Humans
  • Immunoglobulin M / analysis*
  • Male
  • Methods
  • Pregnancy
  • Rheumatoid Factor / analysis*
  • Time Factors


  • Immunoglobulin M
  • Rheumatoid Factor