COVID-19 STEMI related to microthrombi may lead to coronary microvascular dysfunction

Dalia Aziz; Mehmet Yildiz; Odayme Quesada; Timothy D Henry

doi:10.1002/ccd.30797

COVID-19 STEMI related to microthrombi may lead to coronary microvascular dysfunction

Catheter Cardiovasc Interv. 2023 Oct;102(4):641-645. doi: 10.1002/ccd.30797. Epub 2023 Aug 25.

Authors

Dalia Aziz¹, Mehmet Yildiz¹, Odayme Quesada², Timothy D Henry^{1

2}

Affiliations

¹ The Carl and Edyth Lindner Center for Research and Education at The Christ Hospital, Cincinnati, Ohio, USA.
² Women's Heart Center, The Christ Hospital Heart and Vascular Institute at The Christ Hospital, Cincinnati, Ohio, USA.

PMID: 37622612
DOI: 10.1002/ccd.30797

Abstract

Coronavirus disease 2019 (COVID-19) increases the risk of ST-segment elevation myocardial infarction (STEMI), and is associated with a higher occurrence of nonobstructive coronary artery disease. We present a unique case of STEMI with concomitant COVID-19 infection in a young female found to have slow flow in multiple vessels on angiography, likely due to microvascular thrombi. Three months later, the patient developed coronary microvascular dysfunction (CMD), suggesting an evolution of microvascular thrombi and injury into subsequent CMD.

Keywords: acute myocardial infarction (AMI)/STEMI; angiography (ANCO); coronary; coronary artery disease (CAD).

Publication types

Case Reports