Disease-free survival as the endpoint in multimodal rectal cancer trials: have we got this right?

Affiliations

• ¹ Department of Radiotherapy of Oncology, University of Frankfurt, Frankfurt 60590, Germany; German Cancer Research Center, Frankfurt, Germany; Frankfurt Cancer Institute, Frankfurt, Germany. Electronic address: emmanouil.fokas@kgu.de.
• ² Department of Radiotherapy of Oncology, University of Frankfurt, Frankfurt 60590, Germany; German Cancer Research Center, Frankfurt, Germany; Frankfurt Cancer Institute, Frankfurt, Germany.
• ³ Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
• ⁴ Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Diepenbeek, Belgium; International Drug Development Institute, San Francisco, CA, USA.
• ⁵ Department of Radiotherapy, Mount Vernon Centre for Cancer Treatment, Northwood, Middlesex, UK.