A Family of Related ATP-binding Subunits Coupled to Many Distinct Biological Processes in Bacteria

Nature. 1986 Oct 2-8;323(6087):448-50. doi: 10.1038/323448a0.

Abstract

Many biological processes are coupled to ATP hydrolysis. We describe here a class of closely related ATP-binding proteins, from several bacterial species, which are associated with a variety of cellular functions including membrane transport, cell division, nodulation in Rhizobium and haemolysin export. These proteins comprise a family of structurally and functionally related subunits which share a common evolutionary origin, bind ATP and probably serve to couple ATP hydrolysis to each of these biological processes. This finding suggests a specific role for ATP in cell division, nodulation during nitrogen fixation and protein export, and allows us to assign a probable function to one of the protein components from each of these systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / metabolism*
  • Amino Acid Sequence
  • Bacteria / metabolism*
  • Molecular Weight
  • Protein Binding

Substances

  • Adenosine Triphosphate