In pediatric kidney failure, native kidneys may pose a risk to successful transplant outcomes. The indications and timing of native nephrectomy represent a controversial management decision. A lack of high-quality, outcomes-based data has prevented development of evidence-based guidelines for intervention. In this article, we review the published literature on medical indications for native nephrectomy and current knowledge gaps. In addition, we provide a surgical perspective regarding timing and approach.
Keywords: Kidney failure; Kidney transplantation; Native nephrectomy.
© 2023. The Author(s), under exclusive licence to International Pediatric Nephrology Association.