Background: Perianal malignancies are rare tumors with unique presentations and treatment options.
Objective: To review published literature about primary malignancies that present on perianal skin and published guidelines and treatment options.
Materials and methods: A PubMed search was conducted for original articles about perianal malignancies.
Results: Squamous cell carcinoma, basal cell carcinoma, melanoma, and extramammary Paget disease are the most common tumors to present on perianal skin. Anal squamous cell carcinoma incidence is increasing and certain populations may benefit from screening. Surgical management is often recommended for localized perianal tumors.
Conclusion: Dermatologic surgeons should be familiar with the presentation and treatment options available for perianal malignancies.
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